A non-randomized controlled clinical trial to develop an objective test based on ocular following responses (OFRs) measurement to assess stereoacuity in infants and children

Principal Investigator: Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”

Partner: Bioengineering Group (BioingTS), Department of Engineering and Architecture, University of Trieste

 

Project head: Dott. Stefano Pensiero, Prof. Agostino Accardo
Researcher: Dott.Ric. Aleksandar Miladinovic

 

About 

Stereoblindness is the most common deficit associated with amblyopia; it usually occurs during the first months of life and may have a substantial impact on visuomotor tasks and locomoting safety. Early diagnosis and treatment can lead to better outcomes, yet diagnostic tests for infants are not available (most currently available clinical tests to assess stereoacuity require compliance, and so are poorly suited for screening of children). OFRs measurement is an effective non-invasive tool to assess stereoacuity in adults, requiring only minimal cooperation during recording. We hypothesise that OFRs measurement can be effectively used to screen for stereodeficiencies in children.

 

Aim: The aim of this study is to develop an objective test to assess stereoacuity in children, based on OFRs measurement, and to evaluate its efficacy and sensitivity.

 

Publications:

Miladinović, A., Quaia, C., Ajčević, M., Diplotti, L., Cumming, B. G., Pensiero, S., & Accardo, A. (2022). Ocular-following responses in school-age children. Plos one, 17(11), e0277443.

Quaia, C., FitzGibbon, E. J., Optican, L. M., & Cumming, B. G. (2018). Binocular summation for reflexive eye movements: A potential diagnostic tool for stereodeficiencies. Investigative Ophthalmology & Visual Science, 59(15), 5816-5822.

Quaia, C., Optican, L. M., & Cumming, B. G. (2018). Binocular summation for reflexive eye movements. Journal of Vision, 18(4), 7-7.